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ARICEPT (Donepezil Hcl), a centrally acting reversible acetyl-choline esterase inhibitor is prescribed by the physicians for the treatment of Dementia in Alzheimer’s disease. ARICEPT (Donepezil Hcl) increase the level of acetyl-choline which is necessary for the memory and thinking in the dementia patients. ARICEPT (Donepezil Hcl) inhibits the enzyme that degrades the acetyl-choline thereby it improves the function of brain. ARICEPT (Donepezil Hcl) is usually prescribed for the mild to moderate degree of dementia caused by the Alzheimer’s disease. The oral Bioavailability of ARICEPT (Donepezil Hcl) is 100% and it can cross the Blood-Brain Barrier (BBB) and a half-life of 70 hours. ARICEPT (Donepezil Hcl) can improve sleep apnoea in Alzheimer’s disease patients. Recent research study suggests ARICEPT (Donepezil Hcl) can improve severe Alzheimer’s disease symptoms.
Who should not take ARICEPT (Donepezil Hcl)?
ARICEPT (Donepezil Hcl) should not be prescribed for the patients with Chronic Obstructive Pulmonary Disease (COPD) and asthma, prostatic hypertrophy with or with out malignancy, liver and kidney disorders, convulsive disorders, problems in micturition, gastric or duodenal ulcers, Sinus sick syndrome (Slow heart beat), a heart rhythm disorder, patients with congestive heart failure, patients with surgery in the near future and sleeping disorders. You should not take ARICEPT (Donepezil Hcl), if you are known allergic to the same. According to Food and Drug Administration, ARICEPT (Donepezil Hcl) is a Pregnancy Category – C drug and you should consult your Physician before taking ARICEPT (Donepezil Hcl). If you are breast feeding your infant, you should not take ARICEPT (Donepezil Hcl), as it can pass through the breast milk and harm the feeding infant. You should not take ARICEPT (Donepezil Hcl), if you are taking drugs like NSAIDs like Aspirin, Diclofenac, Ketorolac, Piroxicam like drugs, Mefenamic acid and Ibuprofen, anti-malarial drugs, dicyclomine, hyoscyamine, Phenobarbital, Phenytoin, antifungal drugs like Ketoconazole and itraconazole, atropine and belladonna like drugs, steroids like dexamethasone, carbamazepine and rifampicin. If you are taking any of these drugs before, inform your Physician that you are taking these drugs.
ARICEPT (Donepezil Hcl) Side Effects:
ARICEPT (Donepezil Hcl) can cause side effects like fever, facial flushing, cellulitis, influenza like symptoms, chest pain, abscess, congestive heart failure, deep vein thrombosis, tachycardia, bloody stools, sleep disorders, faecal incontinence, painful micturition, hematemesis (blood vomiting), epigastric distress, dry mouth, nausea and vomiting, loss of appetite, cholelithiasis, gastroenteritis, haemorrhoids, duodenal ulcer, severe diabetes mellitus, goitre, anaemia, fatigue, Eosinophilia, pathological fracture, nerve weakness, nystagmus, skin reactions like pruritis, hematuria, pyuria and seizure like conditions. Most of the symptoms and side effects of ARICEPT (Donepezil Hcl) may vary from person to person.
How should I take ARICEPT (Donepezil Hcl)?
The recommended oral dosage for the ARICEPT (Donepezil Hcl) is 5 mg/day. This dosage can be increased to 10 mg/day after an adjusted dosage period of at least four weeks of duration. The following instruction should be followed to take the ARICEPT (Donepezil Hcl) – 5.0 mg oral dosage daily: (1) Take ARICEPT (Donepezil Hcl) as directed by the Physician, usually in the bed time. 2) Take ARICEPT (Donepezil Hcl) while you are sitting or standing up. 3) Take ARICEPT (Donepezil Hcl) with 6 to 8 ounces (about 1 cup) of plain water. Do not take ARICEPT (Donepezil Hcl) with any other drink besides plain water. Do not take ARICEPT (Donepezil Hcl) with coffee, tea, juice, milk or other dairy drinks. 4) Swallow ARICEPT (Donepezil Hcl) as a whole. Do not chew the tablet or keep ARICEPT (Donepezil Hcl) in your mouth to melt or dissolve. After taking ARICEPT (Donepezil Hcl) you must wait at least 30 minutes BEFORE: 1) lying down. You may sit, stand, or do normal activities like read the newspaper or take a walk. 2) Eating or drinking anything except plain water.
Keep taking ARICEPT (Donepezil Hcl) for as long as your health care provider tells you to do so. To treat your problems or keep you from getting these symptoms, you have to take ARICEPT (Donepezil Hcl) as often and in the way ARICEPT (Donepezil Hcl) as prescribed by your Physician.
What is the important information I should know about ARICEPT (Donepezil Hcl)?
Take ARICEPT (Donepezil Hcl) exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
You can take ARICEPT (Donepezil Hcl) anytime disregard of food intake.
For ARICEPT (Donepezil Hcl) dosage one must follow his doctor's instructions.
If you have any surgery in the near future, you should inform your surgeon that you are taking ARICEPT (Donepezil Hcl).
It is important to take ARICEPT (Donepezil Hcl) regularly to get the most benefit, as directed by the Physician.
You should take ARICEPT (Donepezil Hcl) only one dose a day.
Avoid alcohol while you take ARICEPT (Donepezil Hcl) because it can increase the side-effects caused by ARICEPT (Donepezil Hcl).
Do not take Over-The-Counter (OTC) medicines including NSAIDs while you take ARICEPT (Donepezil Hcl).
Take ARICEPT (Donepezil Hcl) with a full glass of water.
Do not stop taking ARICEPT (Donepezil Hcl) without first talking to your doctor, even if you are feeling well. Even after your symptoms improve, you may require continuous treatment for quite some time, as directed by the Physician.
Store ARICEPT (Donepezil Hcl) as per the instructions on the label.
Keep ARICEPT (Donepezil Hcl) away from the reach of the children and pets.
ARICEPT (Donepezil Hcl) can impair your thinking and reactions. Do not drive vehicles or handle hazardous machineries after intake of ARICEPT (Donepezil Hcl).
What happens if I miss a dose of ARICEPT (Donepezil Hcl)?
Take the missed dose of ARICEPT (Donepezil Hcl) as soon as you remember, during the same day. If you do not remember until the next day, skip the missed dose and take ARICEPT (Donepezil Hcl) next day as routine dose. Do not take a double dose of the medication that can cause serious side effects.
What happens if I overdose of ARICEPT (Donepezil Hcl)?
Please seek emergency medical attention immediately.
Where can I get more information on ARICEPT (Donepezil Hcl)?
ARICEPT (Donepezil Hcl) prescribed patients, who try to place an order for ARICEPT (Donepezil Hcl) from an online pharmacy store, can place their prescription order at the CanadaDrugsOnline.com which is an online Canadian pharmacy store.
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