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DDAVP (Desmopressin Acetate), a synthetic hormone similar to vasopressin is prescribed by the physicians for the treatment of central diabetes insipidus, temporary medical management for the polydypsia and polyuria caused by the head injury or by the surgery in the pituitary region and in nocturnal enuresis (night time bed wetting). The mechanism of action of DDAVP (Desmopressin Acetate) is limiting the urinary output by acting directly in the collecting tubules of the kidneys. DDAVP (Desmopressin Acetate) is also used in the coagulation disorders like the von Willebrand disease and also in the uraemia induced thrombocytopenia. DDAVP (Desmopressin Acetate) can be used as a nasal spray, intravenous injection or as an oral tablet.
Who should not take DDAVP (Desmopressin Acetate)?
DDAVP (Desmopressin Acetate) should not be prescribed for the patients with low blood pressure, familial or personal history of cerebral haemorrhage, coronary artery disease, arterial hypertension, electrolytic imbalance including Hyperkalemia, sleeping disorders and cystic fibrosis. You should not take DDAVP (Desmopressin Acetate), if you are using drugs like epinephrine, norephinephrine, clofibrate, anti-hypotensive drugs and Glyburide. No supportive toxicological scientific evidences available of DDAVP (Desmopressin Acetate) in pregnancy and breast feeding. If you are allergic to DDAVP (Desmopressin Acetate), consult your Physician right away.
DDAVP (Desmopressin Acetate) Side Effects:
DDAVP (Desmopressin Acetate) tablets can cause side effects like depression, stomach upset, electrolyte imbalance, conjunctivitis, arterial hypertension, abdominal pain and rarely hypotension events. DDAVP (Desmopressin Acetate) nasal spray/drops can cause upper respiratory infections, epistaxis (nose bleeding), and lack of tears secretion, pain or irritation in the nose and throat, headache, mild to moderate nausea or vomiting and abdominal cramps. However, most of the other uncommon symptoms may vary from person to person.
How should I take DDAVP (Desmopressin Acetate)?
The recommended oral/nasal/intravenous dosage of DDAVP (Desmopressin Acetate) depends up on the medical condition of the patient, age and the response of the body to the drug. For the treatment of central diabetes insipidus in adults and children aged over 4 years the recommended initial oral tablet dose is 0.1 mg twice daily. The usual and initial recommended adult dose of nasal spray/drops for the treatment of central diabetes insipidus is 0.1 – 0.4 millilitre as a single or divided doses, daily. For the children between 3 to 12 months, the recommended dose is 0.5 – 0.3 millilitre daily as single or divided dose. For the treatment of bed wetting in children aged 6 and over, the recommended dose of DDAVP (Desmopressin Acetate) is 0.2 millilitres, half of the dose in each nostril, as bed time dose. The range of dosage requirement is 0.1 to 0.4 millilitres, according to the requirement. The following instruction should be followed to take the DDAVP (Desmopressin Acetate): (1) Take DDAVP (Desmopressin Acetate) as exactly prescribed by the Physicians. Do not swallow the nasal spray or drops 2) DDAVP (Desmopressin Acetate) delivers 50 metered-dose and you should discard the nasal spray container after 50 standard use 3) If you are switching the route of administration to tablets from nasal spray/drops, you need to wait at least 12 hours after the last nasal dose of DDAVP (Desmopressin Acetate) 4) Swallow DDAVP (Desmopressin Acetate) tablets as a whole. Do not chew the tablet or keep DDAVP (Desmopressin Acetate) in your mouth to melt or dissolve. After taking DDAVP (Desmopressin Acetate) tablets you must wait at least 30 minutes BEFORE: 1) lying down. You may sit, stand, or do normal activities like read the newspaper or take a walk. 2) Eating or drinking anything except plain water.
Keep taking DDAVP (Desmopressin Acetate) for as long as your health care provider tells you to do so. To treat your problems or keep you from getting these symptoms, you have to take DDAVP (Desmopressin Acetate) as often and in the way DDAVP (Desmopressin Acetate) as prescribed by your Physician.
What is the important information I should know about DDAVP (Desmopressin Acetate)?
Take DDAVP (Desmopressin Acetate) exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
The nasal spray of DDAVP (Desmopressin Acetate) is for the intra-nasal use only and you can take only 50 doses of medication. After that, you need to discard the medicine.
You can take DDAVP (Desmopressin Acetate) any time disregard of food intake.
For DDAVP (Desmopressin Acetate) dosage one must follow his doctor's instructions.
If you experience uncontrolled urine output even after taking DDAVP (Desmopressin Acetate), consult your Physician right away.
It is important to take DDAVP (Desmopressin Acetate) regularly to get the most benefit, as directed by the Physician.
Depending on the response of the body to DDAVP (Desmopressin Acetate), your Physician may adjust your dose.
If you are having nasal congestion, running nose, rhinitis or any other nose related acute problems, stop taking DDAVP (Desmopressin Acetate) nasal drops/spray. Consult your Physician for an alternative route of administration.
Limit your fluid intake while using DDAVP (Desmopressin Acetate) to avoid fluid retention or water intoxication.
Do not stop taking DDAVP (Desmopressin Acetate) without first talking to your doctor, even if you are feeling well. Even after your symptoms improve, you may require continuous treatment for quite some time, as directed by the Physician.
Store DDAVP (Desmopressin Acetate) as per the instructions on the label.
Keep DDAVP (Desmopressin Acetate) away from the reach of the children and pets.
What happens if I miss a dose of DDAVP (Desmopressin Acetate)?
Take the missed dose of DDAVP (Desmopressin Acetate) as soon as you remember, during the same day. If you do not remember until the next day, skip the missed dose and take DDAVP (Desmopressin Acetate) next day as routine dose. Do not take a double dose of the medication that may lead to serious side effects.
What happens if I overdose of DDAVP (Desmopressin Acetate)?
Over dose of DDAVP (Desmopressin Acetate) can cause nausea, abdominal cramps and flushing. Try to seek emergency medical attention immediately.
Where can I get more information on DDAVP (Desmopressin Acetate)?
DDAVP (Desmopressin Acetate) prescribed patients, who try to place an order for DDAVP (Desmopressin Acetate) from an online pharmacy store, can place their prescription order at the CanadaDrugsOnline.com which is an online Canadian pharmacy store.
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