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Drug Information: Motilium

MOTILIUM (Domperidone) is prescribed by the physicians for the adult patients with the symptoms of nausea and vomiting, bloating, regurgitation of gastric contents and abdominal discomfort. MOTILIUM (Domperidone) is an anti-dopaminergic medicine that regulates the bowel movements or the contractions of the bowel. MOTILIUM (Domperidone) is a best choice of drug in the treatment of the drug induced nausea and vomiting in Parkinson’s disease. MOTILIUM (Domperidone) does not cross the Blood-Brain Barrier as like the metoclopromide. MOTILIUM (Domperidone) is an effective drug, used in the stomach motility conditions like gastro paresis and paediatric gastro-esophageal reflux, a vomiting condition in the infants. MOTILIUM (Domperidone), which promotes the prolactin secretion, is also for the stimulation of lactation in the breast feeding mothers as an off-label prescription which is not approved by the Food and Drug Administration (FDA).

Who should not take MOTILIUM (Domperidone)?

MOTILIUM (Domperidone) should not be used by the patients with gastric bleeding conditions and other problems involving the bowels, Pheochromocytoma, tumour in the pituitary, liver diseases, elderly patients and MOTILIUM (Domperidone) allergy and known hypersensitive individuals. MOTILIUM (Domperidone) is contraindicated in the patients taking medication for the existing diseases like MAOI (Mono Amine Oxidase Inhibitors), anti-fungal drugs, macrolide antibiotics, HIV Protease inhibitors, nefazodone like drugs and other Over-The-Counter drugs. MOTILIUM (Domperidone) should not be used, if you are nursing mother to a neonate because there is risk of developing seizures in the feeding neonates. If you are taking antacids and anti-secretory agents, it can lower the bioavailability of MOTILIUM (Domperidone). The actions of the MOTILIUM (Domperidone) are antagonised by some drugs like anti-muscarinic agents and opioid analgesics, if taken concomitantly. MOTILIUM (Domperidone) should not be given to the children suffering from Lactose intolerance, galactosemia and glucose or galactose intolerance.

MOTILIUM (Domperidone) Side Effects:

MOTILIUM (Domperidone) can cause serious side effects like the Dystonic reactions like Extra Pyramidal phenomena, abdominal cramps, arrthymia, tachycardia, oedema in the upper and lower extremities and swelling in the mouth. Other less serious side effects of MOTILIUM (Domperidone) are galactorrhoea, dry mouth, pain or discomfort in the breast, menstrual irregularities, allergic hives, swelling in the breast of the male, pruritis (itching) and rarely difficult micturition, palpitations, drowsiness, lack of coordination, heartburn and irritability can occur. But most of these rare side-effects differ from patient to patient.

How should I take MOTILIUM (Domperidone)?

The recommended adult dosage for the MOTILIUM (Domperidone) is 10 - 20 mg daily. The following instruction should be followed to take the MOTILIUM (Domperidone) – 10 - 20 mg once daily but not exceed 80 mg per day: (1) Take MOTILIUM (Domperidone) first thing in the morning before you eat or drink anything except plain water. 2) Take MOTILIUM (Domperidone) while you are sitting or standing up. 3) Take MOTILIUM (Domperidone) with 6 to 8 ounces (about 1 cup) of plain water. Do not take MOTILIUM (Domperidone) with any other drink besides plain water. Do not take MOTILIUM (Domperidone) with coffee, tea, juice, milk or other dairy drinks. 4) Swallow MOTILIUM (Domperidone) as a whole. Do not chew the tablet or keep MOTILIUM (Domperidone) in your mouth to melt or dissolve. After taking MOTILIUM (Domperidone) you must wait at least 30 minutes BEFORE: 1) lying down. You may sit, stand, or do normal activities like read the newspaper or take a walk. 2) Eating or drinking anything except plain water.

Keep taking MOTILIUM (Domperidone) for as long as your health care provider tells you to do so. To treat your problems or keep you away from getting these symptoms, you have to take MOTILIUM (Domperidone) as often and in the way MOTILIUM (Domperidone) as prescribed by your Physician.

What is the important information I should know about MOTILIUM (Domperidone)?

  • Take MOTILIUM (Domperidone) exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • You should take MOTILIUM (Domperidone) at least 15 – 30 minutes before the food intake. If MOTILIUM (Domperidone) is taken after the food can delay the absorption of the drug.
  • For MOTILIUM (Domperidone) dosage you must follow your doctor's instructions.
  • It is important to take MOTILIUM (Domperidone) regularly to get the most benefit, as directed by the Physician.
  • Do not stop taking MOTILIUM (Domperidone) without first talking to your doctor, even if you are feeling well. Even after your symptoms improve, you may require continuous treatment for quite some time, as directed by the Physician.
  • The recommended daily dosage of MOTILIUM (Domperidone) should not exceed 80 mg.
  • Store MOTILIUM (Domperidone) as per the instructions on the label.
  • Keep MOTILIUM (Domperidone) away from the reach of the children and pets.

    What happens if I miss a dose of MOTILIUM (Domperidone)?

    Take the missed dose of MOTILIUM (Domperidone) as soon as you remember, during the same day. If you do not remember until the next day, skip the missed dose and take MOTILIUM (Domperidone) next day as routine dose. Do not take a double dose of the medication.

    What happens if I overdose of MOTILIUM (Domperidone)?

    Please seek emergency medical attention immediately, if you experience difficulty in speaking, disorientation, dizziness, fainting, irregular heartbeat, light-headedness, loss of balance or muscle control after taking the MOTILIUM (Domperidone).

    Where can I get more information on MOTILIUM (Domperidone)?

    MOTILIUM (Domperidone) prescribed patients, who try to place an order for MOTILIUM (Domperidone) from an online pharmacy store, can place their prescription order at the CanadaDrugsOnline.com which is an online Canadian pharmacy store.

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