ZOFRAN ORAL SOLUTION (Ondansetron) is a selective serotonin receptor antagonist that is prescribed in the treatment of chemotherapy, radiation and post-surgery induced nausea and vomiting and other medical conditions that induce nausea or vomiting. ZOFRAN ORAL SOLUTION (Ondansetron) blocks the vomiting centre in the brain by blocking the serotonin receptors and thereby prevents the vomiting. As an off-label use, ZOFRAN ORAL SOLUTION (Ondansetron) is prescribed in abnormal vomiting in pregnancy and in irritable bowel syndrome. These off-label uses of ZOFRAN ORAL SOLUTION (Ondansetron) are not approved by Food and Drug Administration.
Who should not take ZOFRAN ORAL SOLUTION (Ondansetron)?
ZOFRAN ORAL SOLUTION (Ondansetron) is contraindicated in patients with phenylketonuria, abnormal electro-cardiac pathophysiology, bronchospasms, shock, cardiopulmonary problems, and low blood pressure. ZOFRAN ORAL SOLUTION (Ondansetron) should be used with extreme caution in geriatric patients above 65 years. You should not take ZOFRAN ORAL SOLUTION (Ondansetron), if you are taking drugs such as tramadol, antacids, methotrexate, cisplatin, phenytoin, apomorphine, etoposide, alcohol, rifampicin and carbamazepine. According to Food and Drug Administration, ZOFRAN ORAL SOLUTION (Ondansetron) is classified as a pregnancy category – B drug, contraindications and side effects in pregnancy and lactation is still unknown.
ZOFRAN ORAL SOLUTION (Ondansetron) Side Effects:
ZOFRAN ORAL SOLUTION (Ondansetron) can cause dizziness, malaise, fever, severe headache, fatigue, diarrhoea or constipation, increase in transaminase levels with 4-6 fold increase in serum BUN, gynaecological disorders, urinary problems, skin rashes with or without pruritis, low blood pressure, fainting, behavioural changes, angioedema, ECG changes, temporary blindness and hearing problems, dystonia and severe drug allergy.
|
